Objective To analyze the TCM syndromic features of RA-IPF and related influence factors. Methods A case-control study was used to collect clinical data such as basic information, laboratory indices and evidence typing of RA patients through the electronic medical record system. The differences of factors between RA-IPF and RA patients alone were analyzed and the main influence factors associated with RA-IPF were screened out. Results Among the 2 788 patients with RA, there were 115 patients with concurrent IPF. According to the results collected, RA-IPF patients were more likely men who were with older age, faster ESR, higher D-dimer, higher RF-IgA, higher RF-IgM, higher RF-IgG, higher anti-U1-RNP antibodies and higher anti-Jo-1 antibodies(P<0.05). Conclusion RA-IPF may be related to patients’ gender, age, ESR, D-dimer, RF-IgA, RF-IgM, RF-IgG, anti-U1-RNP antibodies, and anti-Jo-1 antibodies. An advanced age is a risk factor for RA-IPF.