Objective To discuss the curative effect of Needle Pricking Therapy and Rotating Pulling Manipulation on blood rheological index and efficacy in patients with lumbar disc herniation(prolapse of lumbar intervertebral disc, LIDP). Methods 206 patients were randomly divided into the observation group, 105 cases and the control group, 101 cases in each group. The observation group was Needle Pricking Therapy and Rotating Pulling Manipulation the nerve root at corresponding segments, and the control group was Rotating Pulling Manipulation. A course of treatment was for 10 times. After 20 times treatment, we compare the changes in F wave velocity, JOA-score and blood viscosity before and after treatments, and observe the nerve root, symptom relief and efficacy of patients. Results There were statistical significance between the therapeutic group and the control group(P<0.01). Conclusion Needle Pricking Therapy and Rotating Pulling Manipulation can significantly improve the pain symptoms or activity degree, At the same time, it can improve the F wave conduction velocity of tibia and peroneal nerve caused by LIDP, reduce the blood viscosity and the F wave conduction velocity of tibia and peroneal in patients with LIDP.