基于络脉瘀阻理论探讨RIF患者子宫内膜血流
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1.云南省妇幼保健院;2.云南省中医医院

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1.温阳健脾法通过CREB/lnc-TMEM44/TLR4信号轴调控复发性流产的母胎 免疫耐受能力的机制研究(82060882);2.基于“冲为血海”理论针药疗法结合黄体支持疗法改善RIF患者子宫内膜血流的临床研究(FYJK2022-05)


Exploring endometrial blood flow in patients with RIF based on the theory of collateral stasis
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1.Yunnan Maternal and Child Health Hospital;2.Renshou Traditional Chinese Medicine Hospital,Meishanshi

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    摘要:

    近年来,随着社会经济的高速发展及婚姻观念的改变,婚育年龄全面推迟,导致全球不孕症的发生率逐年上升。随着辅助生殖技术的快速发展,体外受精-胚胎移植技术成为了不孕不育症患者的福音,使不孕症患者的临床妊娠率明显提高,但仍有部分患者经过多次优质胚胎移植后始终不能成功妊娠,使得患者面临巨大的心理负担和经济压力,因此,寻找更有效的治疗方法来帮助这些患者实现生育愿望迫在眉睫。当前中医药的治疗贯穿辅助生殖全程,本文认为络脉瘀阻与微循环血流有互相耦合的作用,从络脉瘀阻理论探讨出RIF患者的症结所在,从而改善RIF患者子宫内的血流灌注、降低子宫动脉血流阻力,提高患者胚胎种植率及临床妊娠率,为中医精准干预、精准治疗的临床应用与研究提供有力的依据。

    Abstract:

    In recent years, with the rapid development of social economy and changes in marriage concepts, the age of marriage and childbirth has been comprehensively postponed, leading to an increasing incidence of infertility worldwide. With the rapid development of assisted reproductive technology, External fertilization embryo transfer technology has become a blessing for infertile patients, which has significantly increased the clinical pregnancy rate of infertile patients. However, some patients still cannot successfully conceive after multiple high-quality embryo transfers, which makes patients face huge psychological burden and economic pressure. Therefore, it is urgent to find more effective treatment methods to help these patients achieve their reproductive aspirations. The current treatment of traditional Chinese medicine runs through the entire process of assisted reproduction. This article believes that there is a coupling effect between collateral stasis and microcirculation blood flow. From the theory of collateral stasis, the crux of RIF patients is explored, thereby improving blood flow perfusion in the uterus, reducing uterine artery blood flow resistance, increasing patient embryo implantation rate and clinical pregnancy rate. This provides a strong basis for the clinical application and research of precise intervention and treatment in traditional Chinese medicine.

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  • 收稿日期:2023-07-27
  • 最后修改日期:2023-09-20
  • 录用日期:2023-09-22
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