Fibrosis is a common pathway for gouty nephropathy to progression to end-stage renal failure. Based on the TCM theory of pleen and kidney deficiency, water-damp internal retention, phlegm-turbidity accumulation and blood stasis coagulation stagnation, it has been shown to have remarkable clinical effect in the treatment and regulation of gouty renal fibrosis by clearing damp and promoting diuresis. The research concerned on relevant literatures in the past 20 years, which were retrieved in the three Chinese databases of CNKI, WF, VIP and PubMed database, and searched by keywords such as gouty renal fibrosis, gouty nephropathy, traditional Chinese medicine, etc. This article systematically reviews the main pathological mechanisms of gouty renal fibrosis and the latest research progress of clearing damp and promoting diuresis of TCM and compound anti-gouty renal fibrosis，aiming to provide reference and ideas for the treatment of gouty renal fibrosis with TCM clearing damp and promoting diuresis.