Objective:Study on the extraction technology and anti-oxidant activity of Pericarp Polysaccharide from Fructus Gleditsiae abnormalis.Method:Single factor and orthogonal tests were applied to optimize the extraction conditions of polysaccharide from Fructus Gleditsiae abnormalis pericarp,including the ratio of raw materials to solvent,temperature,time.Anti-oxidation was detected with pyrogallol autoxidation and Fenton reaction.Result:The optimum extraction conditions were the ratio of raw materials to solvant 1∶25(w/v),90℃ for 60 minutes.Anti-oxidation tests show that the polysaccharides concentration required to clear 50% O2- ·is 09μg/ml and the concentration required to clear 50% ·OH is 174mg/ml.Conclusion:Pericarp polysaccharides from Gleditsiae abnormalis appear strong antioxidation.