Objection:To provide base data and method for TCM syndrome of Male Climacteric Syndrome researching，we made questionnaire of the disease.Methods:By using method of documentary and investigating the clinical cases and adopting descriptive analysis with statistical package.Results:Through a small range clinical investigation we proved that the questionnaire is rather recapitulative for the syndrome differentiation and symptom sign distribution.Conclusion:The methods are feasible for making the clinical symptom sign questionnaire.The methods provide new thread and approach for TCM syndromes researching of Male Climacteric Syndrome.