Objective：Preliminary study on the effect of Shenling Baizhu powder and Gexia Zhuyu decoction on lipid metabolism in mice. Methods：Mice were preventive given two decoctions for 5 days, and the method of quantitative determination of fecal lipid and sugar absorption test were used to detect the excretion of lipid and absorption of xylose. Results：Gexia Zhuyu decoction could significant stimulate the lipid excretion and inhibit the absorption of xylose. Shenling Baizhu powder had no obvious effect. Conclusion：Blood activating therapy could increase lipid excretion and inhibit absorption. But spleen strengthening therapy had little effect on it.