Objective:To explore the relationship between the different syndromes of Traditional Chinese Medicine(TCM)in Cholasma and socio-psychological factors.Methods:307 of cholasma patients were investigated by questionnaires.These forms consist of Zung Self-rating Depression Scale(SDS),Zung Self-rating Anxiety Scale(SAS),Eysenck Personality Questionnaire(EPQ)and Trait Coping Style Questionnaire(TCSQ).On the basis of SPSS statistics analysis,to observe the difference of the points of the target scales and the different syndromes of TCM in Cholasma.Results:①The stagnancy of liver-Qi was expressed most frequenly according to the differetiation of syndromes of TCM in chloasma.The level of depression and anxiety in the group of stagnancy of liver-Qi was higher than the group of stagnation of dampness caused by insufficiency of spleen-Qi and the group of defiecincy of kidney-Yin.②There were relationship between the different syndromes of TCM in chloasma and socio-psychological factors.The stagnancy of liver-Qi was correlated with the level of anxious positively(P＜001).The stagnation of dampness caused by insufficiency of spleen-Qi was correlated with the level of anxious negatively(P＜001).The defiecincy of kidney-Yin was correlated with the level of depression negatively(P＜001).Conclusion:The different syndromes of TCM in Cholasma have close relation with socio-psychological factors.It proves that the emotional disorder is the main pathogical machanism of chloasma.