Purpose:To observe the clinical effect of Erigeron breviscapus to glaucoma with its intraocular pressure under control.Methods:86 patients were randomly divided into A group with Erigeron breviscapus and B group with placebo, clinical outcomes were follow-up four months after treatment.Results:There was significant increase of A group in mean vision score points(P＜005)after two and four months treatment.The rate of vision progress of A group(3846%)was significant higher than B group(2353%).There was no significant difference of two groups in intraocular pressure,blood pressure, heart rate and hemorheology(all P＞005).Side-effect was also not found in two groups. Conclusion:Erigeron breviscapus has certain effect on treatment of glaucomatous optic neuropathy,and no side-effect was found.