Analyze and discuss the clinical application of Fuzi from 7 aspects:properties, tastes, functions and usage;indication;compatibility;dosage;methods of decocting and taking;adverse reaction and treatment；contraindication.Regard the application of Fuzi targeting at Yinzheng and hanzheng,and its functions of treatment and adverse effects are obvious,so the rational and general application of Fuzi is based on differentiating Yin and Yang,discerning cold and heat.And the rule of deeper academic thought is health preserving,therapy and raising Yangq.Aconition in Fuzi can be toxic,resulting in cardiac arrhythmias;while it also can be effective component,for it can ease pain.The difference in physiology and pathology(physique and Zhenghou)can affect tolerance against Aconition.And diversity in dosage and decocting can affect content of Aconition,further altering toxin and treatment of Fuzi.Therefore,it is necessary to take various factors into consideration before changing the dosage and decocting of Fuzi.