Through mutual knot theory origin phlegm and blood stasis,this article helps to understand each period of mutual phlegm and blood stasis theory and clinical treatment of progress,the authors think phlegm and blood stasis syndrome is the formation of the mutual“by many factors common function and form a pathological state,phlegm and blood stasis and other disease produces mutual and pathological foundation.In addition,qi stagnation,Yang,spleen with phlegm and blood stasis are directly related to the formation of inclusion and clinical manifestation,therefore in unionizing phlegm and blood stagnation,the authors also consider other factors related to the disease.