Abstract:Objective: To optimize the best Extraction process and to investigate its Purification Technology of Bergenin from the Bergama purpurascens(Hook.f.et Thoms.)Engl.Methods:To determine Bergenin content with UV-visible spectrophotometer as an indicator to study the main effect factors of influencing macro-reticular resin purification and ethanol extract technology.Results:Having determined the optimal extraction process of Bergama purpurascens(Hook.f.et Thoms.)Engl.,which include extraction Bergama purpurascens(Hook.f.et Thoms.) Engl.with tenfold 50% ethanol three times,0.5 hour per time, and best purification condition is that loading 2.5 grams net raw medicinal materials at most into D-101 resin each gram and absorb 30mins and the procedure of elution is 6 times 20% ethanol the volume of colume.Conclusion:the content of Bergenin reached 14.023%,which based on The best parameters of purification and extraction,the results are reliable.