Objective: To investigate the clinical efficacy on moxibustion-warmed needling for the non effusion osteoarthritis in the knees. Methods：50 patients of non effusion knee osteoarthritis were randomly divided in two groups. The treatment group (moxibustion-warmed needling ) 25 cases, using moxibustion-warmed needling therapy(choose acupuncture point: xuehai, heding, dubi, liangqiu，lixiyan，yinlingquan，xiyangguan, yaoyangguan, shenshu); The control group in 25 patients received Celebrex(Celecoxib) Capsules by oral.Results: treatment group and control group could relivies painess of non effusion osteoarthritis in the knees. The response rate was 96% in the treatment group and 72% in the control group. There was asignificant defference in clinical efficacy between the two group(P＜001). Conclusion: The curative effecctwas better in the treatment group than in the contral group,and moxibustion-warmed needling is a efficacy method to non effusion osteoarthritis in the knees.