On the basis of family succession and former experience，Professor GUAN Zun-Hui has devoted himself to study on a special way of Acupuncture and Moxibustion. For exploiting and innovating, he has developed the thermal-acupuncture therapy and other special techniques of needling and formed a distinctive GUANs School of Acupuncture and Moxibustion.This article highlights Guan Zun-huis academic thoughts on aspects of differentiationexperience of syndromes of meridian, the principle of GUANs Acupuncture prescription and the essentials of selecting points, GUANs Acupuncture manipulation and academic innovations.