Objective: To research the relativity between Traditional Chinese Medicine syndromes of male climacteric syndrome(MCS) and levels of the sex hormones. Methods: The main Types of syndrome of 562 patients are deficiency of kidney-Yin，deficiency of kidney-Yang，deficiency of heart-Yin，deficiency of heart-Yang，disharmony between heart and kidney，deficiency of liver-Yin and stagnation of liver-Qi. All the patients were drawn 6 ml blood for serum sex hormones test on an empty stomach between eight and ten a.m. Results: Total testosterone of the patients with deficiency of kidney-Yang is lowest than that of other types. There are statistical differences between deficiency of kidney-Yang and other types（P<001）.All the types with the level of total testosterone from the lower to higher are deficiency of kidney-Yang，deficiency of kidney-Yin，deficiency of heart-Yang，deficiency of liver-Yin，deficiency of heart-Yin，disharmony between heart and kidney and stagnation of liver-Qi. There are statistical differences between deficiency of kidney-Yang，deficiency of kidney-Yin，deficiency of heart-Yang and the other types（P<001 or P<005）. The type with highest level of estradiol is deficiency of kidney-Yin. The higher is deficiency of liver-Yin. The types with lower level of estradiol are deficiency of kidney-Yang and deficiency of heart-Yang. There are statistical differences between them（P<005）. The type with highest level of progestin is stagnation of liver-Qi which has statistical differences to others（P<005）. There are no significant differences between PRL，LH and FSH（P＞005）. Conclusion: There is relativity between TCM Syndromes of male climacteric syndrome and individual sex hormones index. It can provide the exact theoretical basis of objective of TCM and improving clinical treatment of male climacteric syndrome by TCM.