Objective:To observe the improved effect of YaJieShaBa on the dysequilibrium alcoholism mice.Methods:To build a model of dysequilibrium of alcoholism mice using roll bar and climbing pole methods.The roll bar time and the number of turns were observed while the climbing pole time and behavioral rating scores during climbing were recorded and evaluated.Results:Mice with 15mL/kg.bw 56° alcohol for dysequilibrium were accepted 3.51g crude drug/kg by intragastric administration.The roll bar time and the number of turns were significantly improved,and climbing pole behavior disorder rating scores were reduced in different degrees after drinking 30,60,90min.Conclusions:YaJieShaBa can significantly improve the state of behavior in mice with dysequilibrium.