Objective:By gathering information about the 2010 version of“Chinese Pharmacopoeia”possession of prescription preparation status reports of adverse drug reactions, provide clinical reference for Possession of prescription formulations for the safe use. Methods:Search The Chinese Journal Full-text Database, Chinese Scientific and Technical Periodicals Database, and the case reports of“Chinese Pharmacopoeia”(2010 edition)contains the twenty adverse possession of prescription preparations which published in domestic literature from 1980 to 2010 were collected. Results:There are literature 51 about adverse possession of prescription preparations from the collected twenties. Conclusion:The possession of prescription formulations may cause digestive system, circulatory system, nervous system adverse reactions, occasional allergic reactions, and sometimes serious Adverse reactions.