Objective To investigate the feasibility of cultivated substituting for wild Psammosilenes Radix and lay foundations for resource protection and sustainable use. Methods To study its morphological characteristics of origin plant, macroscopic, microscopic and physiochemical characteristics used in pharmacognostic identification. Results There is notable similarity among plant morphogenesis，characteristic and microscopical structure. There is similarity among the number and colour of TLC spots，the value of Rf. Conclusion This study preliminary confirmed that the cultivated can be the substitutes of the wild Psammosilenes Radix, and this may be the efficient way for the conservation of the endangered resources.