芪苈强心胶囊治疗慢性心衰疗效评价的Meta分析
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1. 河北以岭医药研究院,河北石家庄 050031;2. 河北医科大学第一医院,河北石家庄 050035

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R256.22

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Meta Analysis of the Efficiency of Qiliqiangxin Capsule Treatment Chronic Heart Failure
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1. Hebei Yiling Medicine Research Institute, Shijiazhuang Hebei 050035; 2. First Hospital of Hebei Medical University, Shijiazhuang Hebei 050031

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    摘要:

    目的对芪苈强心胶囊治疗慢性心衰的疗效进行系统评价;方法查阅近6年发表的芪苈强心胶囊治疗慢性心衰的随机对照试验文献27篇,共2570例,其中对照组1198例,芪苈强心组1372例,对其改善心功能疗效及降低BNP疗效进行Meta分析;结果以改善心功能为疗效指标的文献纳入20篇,结果显示芪苈强心组与对照组比较能明显改善心功能(OR=2.45[1.93,3.10]);以降低BNP为疗效指标的文献纳入10篇,结果显示芪苈强心组与对照组比较能明显降低BNP含量(OR=12.86,P<0.00001);结论芪苈强心胶囊治疗慢性心衰疗效良好,值得临床推广。

    Abstract:

    Objective Evaluating systematically the efficiency of qiliqiangxin capsule treatment chronic heart failure. Methods Viewing 27 CRT literatures which Qiliqiangxin capsule treat chronic heart failure published nearly 6 years. There are 2570 cases including control group 1198 cases and Qiliqiangxin group 1372 cases, then evaluating the efficiency of improving heart function and reducing BNP. Results 20 literatures which evaluate the efficiency of Qiliqiangxin capsule improving heart function show that Qiliqiangxin group can improve heart function evidently than control group(OR=2. 45[1. 93,3. 10]);10 literatures which evaluate the efficiency of Qiliqiangxin capsule reducing BNP show that Qiliqiangxin group can reduce BNP evidently than control group(OR=12. 86,P<0. 00001). Conclusion The efficiency of Qiliqiangxin capsule treatment chronic heart failure is well,and worthing clinical promotion.

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