圆瓣姜花的化学成分研究
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1. 云南中医学院中药学院,云南昆明 650500;2. 中国科学院昆明植物研究所,云南昆明 650201

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R284.1

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基金项目: 国家自然科学基金(NO:81060262),云南省中青年学术技术带头人后备人才项目(NO:2010CI047) 收稿日期: 2013 - 04 - 24 作者简介: 高杰杰(1986~),男,贵州福泉人,在读硕士研究生,主要从事植物化学成分及生物活性的研究。 △通信作者:赵庆,E-mail:qingzhaokm2008@126.com;何红平,E-mail:hehongping@mail.kib.ac.cn


Studies on Chemical Constituents of the Rhizomes of Hedychium forrestii Diels.
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1. Faculty of Pharmacy,Yunnan University of TCM,Kunming Yunnan 650500) (2. State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany, Chinese Academy of Sciences,Kunming Yunnan 650201

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    摘要:

    目的 对圆瓣姜花(Hedychium forrestii Diels.)的根茎部分进行化学成分研究。方法 对圆瓣姜花根茎的95%乙醇提取物经乙酸乙酯萃取。乙酸乙酯萃取物经硅胶、十八烷基硅烷键合相(ODS)、葡聚糖醚凝胶Sephadex LH-20等色谱方法进行分离纯化,并运用MS、NMR等波谱方法鉴定化合物的结构。结果 从圆瓣姜花中分离鉴定了5个化合物,分别为:5-hydroxy-3,7,4′-trimethoxyflavone(I),3,5-dihydroxy-7,4′-dimethoxyflavone(II),5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxy-phenyl)-3-heptanone(III),(5R)-5-hydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-3-heptanone(IV),stigmast-4-en-3-one(V)。结论 5个化合物均为从该植物中首次分离得到。

    Abstract:

    Objective To research the chemical constitutes isolated from the rhizomes of Hedychium forrestii Diels. Methods The rhizomes of H. forrestii Diels. were extracted with 95% ethanol,which was suspended in water and then extracted with ethyl acetate. The ethyl acetate extract was extensively separated over chromatographic methods,including silica gel,octadecylsilane(ODS),and Sephadex LH-20. These compounds were elucidated by extensive spectroscopic analysis(MS,NMR,etc. ). Results five compounds,[5-hydroxy-3,7,4′-trimethoxyflavone(I),3,5-dihydroxy-7,4′-dimethoxyflavone(II),5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxy-phenyl)-3-heptanone(III),(5R)-5-hydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-3-heptanone(IV),stigmast-4-en-3-one(V). ] were isolated and identified. Conclusion Five compounds were all isolated from Hedychium forrestii for the first time.

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