益气温阳法治疗缓慢性心律失常的Meta分析
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1. 河北省新乐市医院,河北新乐 050700;2. 新乐市职工医院,河北新乐 050700

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R256.21

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Meta Analysis of Yiqiwenyang Treatment Bradycardia Arrhythmias
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1. The Hospital of Hebei Xinle, Xinle Hebei 050700,China; 2. The hospital of Workers of Xinle, Xinle Hebei 050700,China

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    摘要:

    目的系统评价益气温阳法治疗缓慢性心律失常的临床疗效和安全性。方法选取以阿托品、舒喘灵等西药为阳性对照的RCT文献14篇,共1014例(试验组556例,对照组458例),对益气温阳法治疗缓慢性心律失常的疗效和安全性进行Meta分析。结果以临床疗效为评价指标的文献共纳入13篇,结果显示益气温阳法治疗缓慢性心律失常的临床疗效明显优于与对照组(OR=4.27[3.04,6.01]);以平均心率为评价指标的文献共纳入3篇,结果显示益气温阳法与西药比较能明显提高平均心率(OR=6.58
    [5.27,7.89]);以不良反应为安全性评价指标的文献共纳入3篇,结果显示益气温阳法不良反应明显少于对照组(OR=0.07[0.02,0.20])。结论益气温阳法治疗缓慢性心律失常安全有效,值得临床推广。

    Abstract:

    Objective To evaluate systematiclly the clinical efficiency and safety. Methods Choosing 14 RCT literatures which positive controlled by medicine such as atropine and aerolin and so on. There are 1014 cases which conclude treatment group 556 cases and control group 458 cases. Evaluate the efficiency and safety of yiqiwenyang treatment bradycardia arrhythmias by Meta analysis. Results Choosing 13 literatures which evaluation standard are clinical efficiency, and the results prompt that the clinical efficiency of yiqiwenyang is super than control group(OR=4. 27[3. 04,6. 01]); There are 3 literatures which evaluation standard are mean heart rate, and the results point out that yiqiwenyang can promote mean heart rate obviously than medicine(OR=6. 58
    [5. 27, 7. 89]); Choose 3 literatures which safety evaluation standard are adverse reaction, and the results point out that the adverse reactions of yiqiwenyang are less than control group obviously(OR=0. 07[0. 02,0. 20]). Conclusion It is safety and efficiency that yiqiwenyang treat bradycardia arrhythmias, and it is worth to generalize.

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