Combined with the literature in detail the etiology and pathogenesis of perimenopausal syndrome and acupuncture-moxibustion treatment of perimenopausal syndrome of specific methods and experimental research. To investigate the acupuncture-moxibustion treatment of perimenopausal syndrome. acupuncture treatment of perimenopausal syndrome clinical efficacy significantiy， in some ways hasa great deveiopment potential.