Objective To observe the pharmaceutical cassia twig fibroids pill combination hot ironing therapy on the influence of blood rheology in patients with chronic pelvic inflammatory disease. Methods 100 cases of chronic pelvic inflammation patients were divided into two groups， the treatment group oral cassia twig fibroids pill（10 g cassia twig， cortex moutan 10 g， peach kernel， 10 g， red sage root， 10 g， red paeony root， 10 g， poria cocos 20 g）with hot iron therapy.Antibiotics， a 3 point control static observation curative effect after treatment. Results Team and whole blood treatment group after treatment， whole blood high cutting， plasma viscosity， erythrocyte aggregation index， fibrinogen is on the decline， but the fall of treatment group was significantly greater than the control group， compared two groups before and after treatment， statistically significant difference （P<0.05）. Conclusion Guizhi fibroids pill with hot irons in improve hemorheology in patients with pelvic inflammation effect significantly.