Kidney pathological diagnosis plays a very important role on prognosis and treatment of IgAN. The Renal pathology combined with syndrome differentiation of traditional Chinese medicine is the future direction of Chinese medicine treatment of IgAN. It can make the syndrome more accurate， curative effect more exact. Through reviewing literature of recent years， we summarize IgAN renal pathology of microcosmic syndrome differentiation research to explore effective microcosmic syndrome differentiation methods and the microcosmic syndrome differentiation rule of IgAN.