Objective To study the relationship of immunoglobulins（IgA， IgG， IgM）、T cell subsets（CD3+， CD4+， CD8+， CD4+/CD8+） and children with recurrent respiratory infection in the Lung-spleen-qi-deficiency， spleen-deficiency-hyperactive-liver-fire. Methods We detected 150 cases in the Lung-spleen-qi-deficiency and 150 cases in the spleen-deficiency-hyperactive-liver-fire of RRTI in no nacute infection period of serum IgA， IgG， IgM and CD3+， CD4+， CD8+， CD4+/CD8+ level. A total of 220 children were selected as health control group. Results ①Compared with healthy control group， the level of IgA， IgG and CD4+ cells in the different types of RRTI group decreased（P<0.05）， the percentage of CD8+ cells increased（P<0.05）， CD4+/CD8+ ratio decreased， and there was a significant difference（P<0.01）. No significant differences were foud in other indexes（P>0.05）. ②Compared with the two Chinese medicinesyndromes， the level of IgA， IgG， IgM， CD3+， CD4+， CD8+ and CD4+/CD8+ showed no significant difference（P>0.05）. Conclusion In children of recurrent respiratory tract infection（non-acute infection period）， the syndrome type of traditional Chinese medicine and immune globulin， T cell subsets in microcosmic indexes have a certain correlation， but no significant positive or negative correlation.