Objective Comparison of the Saponins content of Panax notoginseng stems and leaves， and to provide technical support for the quality of related products. Methods Rb3 content was used as indicator to compare the difference between the leaves and stems of Panax notoginseng by HPLC. Results The leaves’ main components are Ginsenoside Rb3， Rc， Fc， et al. and the stems’ main component is Ginsenoside Rb1. Conclusion The main saponin components in leaves and stems have significant difference， in order to ensure the stable quality of product we should pay attention to the selection of raw material， control the proportion of leaf and stem of Panax notoginseng.