Phlegm retention， blood stasis is blood， tianjin is the pathological products of no return， also some risk factors of incurable diseases， knot disease， phlegm and blood stasis sluggish winding loss of arteries and veins， cementation， gradually into the beehive capsule， because its clinical manifestation is complicated， more and more attention in recent years. But with the development of science and technology， the study of part of the theory of TCM has entered the cell biology and molecular level. In this paper， through literature review， combined with clinical experiment， trying to from the perspective of Chinese and western medicine combined with phlegm and blood stasis and vascular endothelial cells.