The therapeutic effect of a certain formula is not only associated with its dosage， but also closely linked with patient’s constitution. Different body constitutions may have different reaction and tolerance to drug. The determination of dosages and types of herbs used were based on constitution differentiation is conducive to minimize adverse reactions and enhance therapeutic effect of a formula. Treatment model is thus converted from the “disease-medicine” model to “constitution-disease-medicine” model， which can guide the clinical dosing of drugs and prevent diseases in an effective way.