Through sorting and analyzing Chinese medicine， etiology， pathogenesis， treatment of 36 stroke basis in CHEN Xiuyuan Medical Cases of Nan Ya Tang to summarize the principle of herbs used. CHEN thought etiology of stroke is “the six evils”， pathogenesis of stroke is qi-blood disturbance， healthy energy-evil struggle， imbalance of Yin and Yang， and advocates to treat with replenishing method， give priority to benefit qi and blood. And CHEN summed up the basic therapeutic principles of stroke prostration and stroke excess from a large number of clinical practice. Drug use detailed.