Objective To observe the clinical curative effect of Qinghuatangyu decoction on the rehabilitation treatment of nonalcoholic fatty liver disease. Methods 60 cases of patients were randomly divided into the treatment group and the control group on average， the treatment group given 6 months’ treatment of Qinghuatangyu decoction combined with polyene phosphatidylcholine capsules（Essentiale）， the control group was given only 6 months’ treatment of Essentiale. Observe both of two groups’ improvements of the symptoms， the liver function， blood lipid and liver/spleen CT ratio in pretherapy and post-treatment. The patients of two groups were suitable to enhance physical exercise and control diet during treatment. Results The total effective rates of treatment group and control group were 86. 7% and 73. 3% respectively， the treatment group is better than that of control group（P<0.05）. After treatment for 6 months， the changes of treatment group’s ALT， AST， GGT、 TC、 HDL-C、 UA、 TNF， liver/spleen CT ratio are better than that of control group（P<0.05）. Conclusion There is a better clinical curative effect of Qinghuatangyu decoction on the rehabilitation treatment of nonalcoholic fatty liver disease， which can significantly improve the patients’ TCM symptoms， liver function， blood fat， serum uric acid， tumor necrosis factor and liver/spleen CT ratio.