Objective To explore the correlation between TCM pathological factors and epidemiological characteristics of methamphetamine addicts. Methods Collecting the information of four diagnostic methods of 121 cases voluntary surveys methamphetamine addiction drug addicts， epidemiological characteristics investigation， using the acquisition method of extracting syndrome factor differentiation TCM elements. And to analyze their relevance. Results 1. Methamphetamine drug addicts manner（oral） in the spleen， heart， qi stagnation， heat， moisture， blood was significantly associated public security group， and is a risk factor；significantly associated with a voluntary group with spleen， stomach exists， and is a protective factor； 2. After the extent of drug contradiction with family and friends in the public security group associated with the presence of liver；voluntary group associated with the presence of mind， and are risk factors. Conclusion The need for social and psychological rehabilitation institutions to intervene into force fluctuations， the lifting of “addiction. ” Oral methamphetamine addicts great impact on the stomach， rehabilitation work can be considered as a fundamental to the spleen and stomach， liver qi stagnation is added， the town of Anshen of the law， effectively reduce the relapse rate.