30 Cases Clinical Observations on the Effect of Zhuye Shigao Decoction on Treating the Vomiting due to the Chemotherapyfor Lung Cancer of Deficiency of Stomach Yin Type
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People’s Hospital of Huanghua City， Huanghua 061100， China
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摘要:
目的 观察竹叶石膏汤治疗肺癌胃阴亏虚型化疗呕吐的临床疗效。方法 将60例肺癌胃阴亏虚化疗呕吐患者按照数字抽签法随机分为2组。对照组30例采取甲氧氯普胺进行止吐治疗，治疗组30例在对照组治疗基础上采用竹叶石膏汤治疗。观察至化疗后第7天临床疗效、恶心呕吐情况及不良反应率，并观察2组治疗前后均对患者进行生活质量（quality of life， QOL）评分。结果 治疗组临床疗效优于对照组，差异具有统计学意义（P<0.05）；治疗组恶心呕吐分度轻于对照组（P<0.05）；治疗组不良反应率低于对照组（P<0.05）。2组治疗后生活质量均有一定的改善（P<0.05），治疗组治疗后QOL评分明显高于对照组（P<0.05）。结论 竹叶石膏汤治疗胃阴亏虚型化疗呕吐疗效显著，能有效改善患者的呕吐症状。
Abstract:
Objective To observe the clinical efficacy of Zhuye Shigao decoction on treating the vomiting due to the chemotherapy for lung cancer of deficiency of Stomach Yin type. Methods 60 such patients under chemotherapy were equally randomized into 2 groups as control and treatment. Control group was given Metoclopramide for stopping vomiting. Metoclopramide and Zhuye Shigao decoction was applied to treatment group. Clinical efficiency， nausea and vomiting as well as adverse reaction rate after 7 days of treatment were recorded. The patients’ Quality of life（QOL） were assessed before and after treatment. Results Treatment group statistically outweighed control group in better clinical efficacy（P<0.05）， slighter nausea and vomiting（P<0.05）， lower adverse reaction rate（P<0.05） and higher QOL scoring（P<0.05）. Both groups received improvement in QOL assessment（P<0.05）. Conclusion Zhuye Shigao decoction is efficient in treating the vomiting due to the chemotherapy for lung cancer of deficiency of Stomach Yin type.