Abstract:The treatment of spinal cord injury is a worldwide problem. Chinese traditional compound Buyang Huanwu decoction with respect to hormones and other drugs in the treatment of spinal cord injury get the advantage of the overall improvement, such as multi-channel and multi-target improve microenvironment of the injured spinal cord. The Buyang Huanwu Decoction improve micro environment of the injured spinal cord research mainly focus on improving the level of free radicals, inhibiting the glutamate excitotoxicity, inhibiting the expression of chondroitin sulfate proteoglycans and glial fibrillary acidic protein expression, up regulating the neuropeptide substance P, decreasing the aquaporin-4 expression after spinal cord injury and inhibiting the platelet activating factor receptor expression.