Objective To observe the tongdu adjustable god electroacupuncture on the neural plasticity in rats with cerebral infarction and explore its mechanism， and to provide experimental evidence for the treatment of ischemic cerebrovascular disease. Methods Choose SPF male 64 rates， weight 250~280g rats. The experimental rats were divided into four groups， 16 rats in every group. Each group were randomly divided into 7d， 14d two sub group， 8 rats in each sub group. Cerebral infarction model was prepared by electric coagulation method. electroacupuncture group acupuncture GV20， GV26， GV14 and GV24， 30 minutes for each time. Model group， sham operation group and normal control group were given the same time bound and fixed not acupuncture treatment. The immune group of method to detect GAP-43 expression， by JD801 morphological image analysis system were analyzed and the results were statistically analyzed. Results No GAP-43 positive cells in normal control group and sham operation group， Model group at 7 and 14 days two time points compared with the sham operation group had significant meaning（P<0.01）； Compared with electric acupuncture treatment group， model group at 7 d and 14 d two time points GAP-43 positive cells in electric acupuncture group were compared with model group， and the difference between the two groups have significant meaning（P<0.01）. Conclusion The expression of GAP-43 in brain tissue of rats with cerebral infarction was promoted by the regulation of the tongdu adjustable god electroacupuncture.