TCM unguent refers to semi-solid topical formulations， constituted by medicine， medicine powder， herbal extract and suitable matrix. In the present， it is the focus of research at home. The quality and stability of TCM unguent have important influence on its performance. This article summarizes the research progress and development of TCM unguent in recent years， including the selection of matrix， quality standard and its stability. Problems related to quality and stability of TCM unguent are discussed in this overview， So as to provide reference for the quality and stability of TCM unguent.