耳穴结合中药防治糖尿病前期的疗效观察
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安徽中医药大学,安徽 合肥 230012

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R246.1

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* 基金项目: 安徽中医药大学2015国家级创新创业项目(2015017)
收稿日期: 2017 - 02- 28
作者简介: 崔圣玮(1995-),女,安徽合肥人,在读本科生,研究方向:中医药治疗内分泌疾病。
△通信作者:吴传云,E-mail:961051255@qq.com


Curative Effect of Auricular Plaster Therapy Combined with Traditional Chinese Medicinein the Prevention and Treatment of Prediabetes
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Anhui University of Traditional Chinese Medicine, Hefei 230012, China

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    摘要:

    目的〓观察耳穴贴压结合中药对糖尿病前期患者干预的效果。方法〓糖尿病前期患者90例,随机分为对照组和治疗组,各45例。对照组给予饮食、运动指导及糖尿病健康教育等一般生活干预;治疗组在一般的生活干预基础上,予耳穴贴压结合中药(十味玉泉胶囊)治疗,并观察两组患者治疗前后的空腹血糖(FPG),餐后2h血糖(2hPBG),糖化血红蛋白(HbAlc)、总胆固醇(TC)、胰岛素抵抗指数(HOMA-IR)、体重指数(BMI)的变化。结果〓两组患者干预后,糖尿病前期逆转率,治疗组明显优于对照组(P<0.01),有显著性差异,而糖尿病的新发率比较无统计学意义(P>0.05)。两组患者FPG、2hPBG、HbAlc、TC、HOMA-IR、BMI治疗后均较治疗前下降(P<0.05,P<0.01),差异有统计学意义;两组间相比较,治疗组患者干预后FPG、2hPBG、HbAlc、TC、HOMA-IR优于对照组(P<0.05,P<0.01),尤以TC、HOMA-IR下降明显(P<0.01),差异有统计学意义。但两组间BMI干预后比较无统计学差异(P>0.05)。结论〓耳穴贴压结合中药十味玉泉胶囊对糖尿病前期的干预,能调节糖脂代谢,降低血糖与血脂,改善胰岛素抵抗,促进患者指标向正常糖耐量逆转,减少糖尿病的发生,较单纯的生活干预有更好的疗效。

    Abstract:

    Objective To observe the effect of auricular plaster therapy combined with traditional Chinese medicine on prediabetes. Methods 90 patients with prediabetes were randomly divided into control group and treatment group, each with a report of forty-five cases. The control group received general life intervention, including diet and exercise guidance, and diabetes health education; the treatment group was given Auricular Pressure Combined with traditional Chinese medicine(ten kinds of Jade Spring capsules) treatment based on the general life intervention. Fasting plasma glucose(FPG), postprandial 2H blood glucose(2hPBG), glycosylated hemoglobin(HbAlc), total cholesterol(TC), insulin resistance index(HOMA-IR), and body mass index(BMI) before and after treatment in the two groups were observed. Results The reverse rate of prediabetes of the treatment group was significantly better than that of control group after treatment(P<0.01), while there was no significant difference between the two groups in the incidence of diabetes mellitus after treatment(P>0.05). The FPG, 2hPBG, HbAlc, TC, HOMA-IR, and BMI in the two groups significantly decreased after treatment(P<0.01). The FPG, 2hPBG, HbAlc, TC, and HOMA-IR of the treatment group were significantly better than those of control group after treatment(P<0.01), while there was no significant difference between the two groups in BMI(P>0.05). Conclusion Auricular Pressure Combined with traditional Chinese medicine intervention in prediabetes, can reduce blood glucose and blood lipids, improve insulin resistance, promote the reversal of normal glucose tolerance, and reduce the incidence of diabetes, which is better than the simple life intervention.

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