Objective To understand college students of TCM Constitution， emotional state distribution， and explore the relationship between the onset pasition of acne. Methods Doing a survey of the 306 college students with the self-made questionnaire on acne patients in Fuzhou. The position of acne， emotional state and constitution of traditional Chinese medicine were analyzed by SPSS20.0 software. Results The cheeks and forehead as was the highest， the chin and nose around secondly，the other parts least. No depression accounted for 55.9% of mood state， depression accounted for 44.1%， mild to moderate depression. Most types of moderate physical quality accounted for 48.4%， accounted for 51.6% of the biased constitution， the top three of the constitution is Qi deficiency， Yang deficiency， Yin deficiency. The attack on the chin and no depression negatively related,with mild depression， severe depression was positively related. The attack on the chin is negatively correlated with peace quality， positive correlation with Qi stagnation and phlegm dampness. Conclusion The prevalence of acne in Fuzhou area of college students is not optimistic， the emotional state of poor physique level needs to be improved， and there are correlation with no types of acne attack locations have depression emotion and physical relevance.