Objective To study the relationship between TCM syndrome differentiation and Hp infection in precancerous lesions of gastric cancer. Methods To collect the TCM syndrome differentiation types of 151 cases according to the diagnostic criteria of plgc， and to explore the relationship between the TCM syndrome differentiation of plgc and HP infection. Results （1） The proportion of blood stasis blood stasis in plgc was the highest（30.47%）， followed by stomach-Yin deficiency syndrome（25.83%） and liver-stomach disharmony syndrome（8.61%）. （2）The number of positive cases of Hp infection in plgc was from high to low， followed by other syndromes>spleen and stomach damp heat syndrome>liver and stomach disharmony syndrome>spleen and stomach weakness syndrome>stomach collaterals blood stasis syndrome>stomach Yin deficiency syndrome. Among them， the stomach Yin deficiency syndrome and the stomach collaterals blood stasis syndrome infection rate is the lowest， and other syndromes have obvious difference， the residual syndrome type of liver stomach disharmony syndrome and the spleen and stomach damp heat syndrome infection rate is higher， and the spleen and stomach weak syndrome have significant difference. Conclusion There is a certain correlation between TCM syndrome differentiation and Hp infection before gastric cancer.