Objective To observe clinical effects on lumbar intervertebral disc herniation（LIDH） before and after treatment with knife needle and regulating Dai meridion， recanalizating Du meridion. Methods Eighty patients were located into two groups randomly： treatment group（40 cases） and control group（40 cases）. The treatment group was treated with knife needle and tuina by regulating Dai meridion， recanalizating Du meridion. The control group was only treated with tuina by regulating Dai meridion， recanalizating Du meridion. Knife needle treatment was given one time per five or seven days according to patients’ state， generally one to five times. Tuina therapy was given every other day， three times each week. The two groups both were observed for four weeks. The differences of clinical effects colligation scores， sagittal diameter index（SI） and curative times before and after treatment in two groups were analyzed， comparing the clinical curative effects of two groups. Results After the treatments， the SI decreased both in two groups. But there was no significantly statistical difference（P>0.05）. The clinical effects colligation scores and curative times of treatment group were remarkably lower than the control group（P<0.05）. The cure rate（48.64%）， total effective rate（97.73%） of clinical efficacy both were higher than control group. Conclusion Comprehensive treatment of knife needle and tuina by regulating Dai meridion， recanalizating Du meridion could effectively improve or relieve the dysfunctions of patients with LIDH. It was superior to control group in quicker effect， shorter treating time.