体质因素对代谢综合征影响的回归分析
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福建中医药大学,福建 福州 350122

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R259

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* 基金项目: 福建省自然科学基金青年创新课题(2016J05194);福建省中青年教师教育科研课题(JA15249);福建中医药 大学校管课题(X2013020)
收稿日期: 2017 - 09- 02
作者简介: 童伯瑛(1980-),女,河南郑州人,讲师,研究方向:中西医结合治疗慢性病。
△通信作者: 游世晶,E-mail:yixiao4211@163.com


Regression Analysis of the Effects of Physical Factors on Metabolic Syndrome
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College of Fujian University of TCM, Fuzhou 350122, China

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    摘要:

    目的 考察中医体质类型对代谢综合征患者发病的影响,为代谢综合征的体质筛查及预防研究提供依据。方法 采用病例-对照研究方法,以60例代谢综合征患者为研究对象,以60例健康体检者为正常对照。以单因素logistic回归分析、多因素logistic回归分析探讨性别、年龄、家族史、职业、文化程度、吸烟、饮酒、嗜肥甘厚味、运动锻炼、精神紧张、体质类型等自变量与代谢综合征的相关性,分析体质因素的作用规律。结果 单因素Logistic回归分析:自变量痰湿质(OR=23.727,95%CI=8.223-68.461)、阴虚质(OR=5.515,95%CI=2.185-13.925)、气郁质(OR=3.574,95%CI=1.374-9.299)OR值大于1,被选入模型。多因素logistic回归分析:痰湿质、饮酒与代谢综合征关联性极高,对应的比数比分别为:20.016、19.834。积极的运动锻炼与代谢综合征的发病成显著性负相关,比数-38.115。 结论 痰湿质、阴虚质、气郁质是代谢综合征主要体质相关因素;吸烟、饮酒、嗜肥甘厚味、精神紧张、家族史与代谢综合征患者呈正相关,是代谢综合征发病的危险因素;运动锻炼与代谢综合征呈负相关性。

    Abstract:

    Objective To explore the distribution of constitutional types in patients with metabolic syndrome under the guidance of the theory of constitution in Chinese medicine, so as to provide an objective basis for the prevention and treatment of metabolic syndrome. Methods Using the case-control research method, 60 patients under the diagnostic standard of metabolic syndrome were studied with 60 healthy check-up people as normal controls. With the single-factor logistic regression analysis and multivariate logistic regression analysis, this study explores the correlation between independent variables(such as gender, age, family history, occupation, education level, smoking, drinking, greasy and thick diet, exercise, mental stress and physical type) and metabolic syndrome, and clarifies the influence of physical type in causal factors of metabolic syndrome. Results single factor logistic regression analysis shows that independent variables phlegm-wetness type(OR=23.727, 95%CI=8.223-68.461), yin-deficiency type(OR=5.515, 95%CI=2.185-13.925), qi-depression type(OR=3.574, 95%CI=1.374-9.299) were selected as model. Multivariate logistic regression analysis showed that phlegm dampness, alcohol consumption and metabolic syndrome were highly correlated, and the corresponding odds ratios were 20.016 and 19.834, respectively.Positive exercise has a significant negative correlation with the incidence of metabolic syndrome, with the ratio of -38.115. Conclusion Phlegm-wetness type, yin-deficiency type and qi-depression type are the main constitution related factors of metabolic syndrome.Smoking, drinking, greasy and thick diet and mental stress are positively correlated to metabolic syndrome, and are risk factors in the pathogenesis of the disease, while exercise and metabolic syndrome had a negative correlation.

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