Objective To observe the clinical effect of electroacupuncture at Jiaji acupoint in the treatment of ankylosing spondylitis. Methods In 108 cases of ankylosing spondylitis patients in January 2014~2017 in January in our hospital as the research object， randomly divided into observation group and control group， 54 cases in each group， the observation group were treated by electroacupuncture at Jiaji acupoint， the control group was treated with conventional treatment of Western medicine. After treatment， the treatment effect， symptom improvement and laboratory index of the two groups were evaluated and compared. Results（1） The total clinical effective rate of the observation group was 92. 59%， and the total clinical effective rate of the control group was 77.78%， and the difference between the groups was statistically significant（P<0.05）. After the treatment the observation of TCM symptom score， visual analogue score group（VAS）， time of morning stiffness were lower than that of control group， spine， thoracic activity is higher than that of the control group， there were significant differences between the two groups（P<0.05）. After treatment， the erythrocyte sedimentation rate（ESR） and C reactive protein（CRP） of the patients in the observation group were lower than those of the control group， and there was a significant difference between the groups（P<0.05）. Conclusions Compared with conventional western medicine， electroacupuncture at Jiaji acupoint has better clinical effect in treating ankylosing spondylitis. It can significantly improve the clinical symptoms and laboratory indicators of patients.