基于中医传承辅助系统的耳鸣耳聋内治方剂组方规律分析*
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山东中医药大学,山东 济南 250000

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R276.1

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收稿日期: 2018 - 02- 18 * 基金项目: 国家级大学生创新创业训练计划项目(201610441038) 第一作者简介: 罗伟康(1996-),男,在读本科生,研究方向:中药组方规律。 通信作者: 张艳,E-mail:zhangyanzelda@163.com


Analysis on Internal Treating Composition Principles of Tinnitus and Deafness by Using Traditional Chinese Medicine Inheritance Support System
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Shandong University of Traditional Chinese Medicine, Jinan 250000, China

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    摘要:

    目的探讨耳鸣耳聋相关内治方剂的组方规律。方法提取《中医方剂大辞典》中耳鸣耳聋内治方剂,建立方剂数据库。运用中医传承辅助系统(V2.5)内置算法进行数据挖掘,分析其组方规律。结果共筛选耳鸣耳聋内治方剂260首,用药261味。用药频次分析中,石菖蒲、甘草、茯苓、当归、附子、川芎、熟地黄、防风、人参、磁石居于前10位;药物归经中,以肝、肾、心、脾、肺归经频次居多;支持度个数≥30的药物模式7个,置信度≥0.5的关联规则4个,均以熟地黄-茯苓组合最高;演化得到核心组合18个,新方剂9首。结论耳鸣耳聋治疗应依据虚证、实证、虚实夹杂的不同病性合理选药;方药配伍时不可只涉及单一脏腑,应多脏腑联合用药,且多以心脾、心肾、心肝、脾肾等多脏腑共治。运用中医传承辅助系统得出的耳鸣耳聋内治方剂组方规律确实对临床有指导意义。

    Abstract:

    Objective To explore the group rule of treating tinnitus and deafness. Methods To extract the prescriptions of traditional Chinese medicine dictionary of tinnitus deafness in prescription, prescription databases, the use of Traditional Chinese Medicine Inheritance Support System (V2.5) built-in algorithm in data mining, analyze its characteristics. Results The total number of tinnitus was 261. In the analysis of drug frequency, the stone calamus, liquorice, poria cocos, angelica, aconite, chuanxiong, ribosome, anti-wind, ginseng and magnetic stone were in the top 10. The drug is attributed to the liver, kidney, heart, spleen and lung. There were 7 drug models with more than 30 support degrees, and the confidence level was greater than 0.5, and all of them had the highest combination of ricosa and poria. Evolution got 18 cores and 9 new prescriptions. Conclusion The treatment of tinnitus deafness should be based on virtual syndrome, empirical and virtual inclusion of different diseases. The combination of prescription should not only involve the single viscera, but should be combined with the internal organs and the heart, the heart, the heart, the liver, the spleen and kidney and so on. The use of traditional Chinese medicine inheritance support system to obtain the prescription of tinnitus in the ear deafness is really helpful to clinic.

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