数据挖掘慢性化脓性骨髓炎的中药处方规律*
作者:
作者单位:

(1. 佛山市中医院,广东 佛山 528000;2. 广州中医药大学,广东 广州 510405)

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R274.9

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收稿日期: 2018 - 05- 28 *
基金项目: 国家级大学生创新创业训练项目(201510572019)
第一作者简介: 刘艳(1983-),女,主管技师,研究方向:骨科疾病的中医护理和康复治疗。
△通信作者: 林海雄,E-mail:lhxiong@foxmail.com


Principles of Chinese Medicine for Chronic Suppurative Osteomyelitis:A Data Mining Study
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Affiliation:

(1. Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, China; 2. Guangzhou University of Chinese Medicine, Guangzhou 510405, China)

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    摘要:

    目的数据挖掘慢性化脓性骨髓炎的用药规律。方法电子检索CNKI、万方及维普数据库中慢性化脓性骨髓炎的用方, 用“中医传承辅助平台V2.5”软件分析。结果纳入100条方,涉及162味中药,4味高频中药依次为当归、黄芪、甘草、金银 花,常用药物组合12对,以补气养血、清热解毒为主,核心药物关联性网络为金银花、蒲公英、紫花地丁、甘草、黄芪、 党参、白术、茯苓、当归,中药四气以温寒为主,五味以甘苦为主,主要归肝脾心经,新方组合11条。结论慢性化脓性骨 髓炎用药从肝脾心入手,法以补气透邪、清热解毒,方以五味消毒饮合四君子汤加减。

    Abstract:

    Objective To analyze the principles of Chinese medicine for chronic suppurative osteomyelitis (CSO)based on data ming. Methods Electronic retrieval of CNKI, Wanfang and VIP database, then extract the prescriptions of CSO. The data was analyzed by the Traditional Chinese Medicine inheritance support system(TCMISS). Results A total of 100 prescriptions, including 162 kinds of herbs, was analyzed. Four drugs, such as Jinyinhua, Huangqi, Danggui, and Gancao were most frequently used. Twelve herbs, which focus on tonifying qi and engendering blood, clearing heat and drawing out toxin, were commonly combined together. Jinyinhua, Pugongying, Zihuadiding, Gancao, Huangqi, Baizhu, Fuling and Danggui were in the core drugs correlation network. The qi and taste of Chinese herbs are mainly warm, cold, sweet, and bitter. The channels were mainly belong to liver, spleen and heart. At the same time, 11 new drug combinations were excavated. Conclusion The CSO treating from liver, spleen and heart. Specific methods including removing heat to eliminate toxins, benefiting qi to activate blood circulation and expelling pathogen. Antiphlogistic decoction of five drugs and decoction of four mild drugs were advocating to treat CSO.

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