Objective To investigate the therapeutic effect of modified Yupingfeng San on Lung deficiency-cold type AR patients， and the influence of peripheral blood Th17/Treg cells characteristic factor IL-17A， TGF-β1 expression. Methods The selection of the treatment of 19 cases of lung deficiency-cold type AR patients， 10 healthy volunteers as control group， of patients with AR deficiency type classification and dividing into 4 groups： Mild intermittent AR、 Moderate to severe intermittent AR、 Mild persistent AR and Moderate to severe persistent AR， modified Yupingfeng San for the treatment of 14d， treatment before and after the score and to evaluate its clinical efficacy， the expression of serum IL-17A， TGF-β1 and ELISA were detected before and after treatment. Results The scores of VAS， TNSS， TNNSS and RQLQ were significantly lower than those before treatment after the treatment of modified Yupingfeng San（**P<0.01）. 19 cases of lung deficiency-cold type AR patients IL-17A and TGF-β1 expression was significantly higher than the control group（**P<0.01）， different classifications and grades of lung deficiency-cold type AR patients， moderate to severe intermittent， mild persistent and moderate severe persistent AR group IL-17A and TGF-β1 expression was significantly higher than the control group（**P<0.01， *P<0.05）， mild intermittent group IL-17A expression was significantly higher than the control group（*P<0.05）， and mild intermittent AR group TGF-β1 expression no difference the control group（*P>0.05）. The expression of IL-17A and TGF-β1 in moderate to severe intermittent， mild persistence and moderate to severe persistent AR group was significantly higher than that of mild intermittent AR（*P<0.05）. After treatment， the expression of IL-17A and TGF-β1 decreased. The expression of IL-17A and TGF-β1 in the treatment group was significantly lower than that in the AR group before treatment， with statistical difference（**P<0.01， *P<0.05）. Conclusion Patients with lung deficiency-cold type AR， modified Yupingfeng San prescription treatment， mucosal edema， inflammation and nasal itching， sneezing， rhinorrhea symptoms improved， gauge score was significantly reduced， the immune imbalance of Th17/Treg improved effect of modified Yupingfeng San of lung deficiency-cold type AR patients have clinical curative effect and regulation the immune imbalance of Th17/Treg.