Objective To establish a method for determination of 5 coumarins in the Angelica Dahurica from Sichuan which with different processing methods and areas by ultra-performance liquid chromatography（UPLC）. Methods The determination was performed on Agilent Eclipse Plus C18 column（2.1 mm × 100 mm， 1.8 μm） with gradient elution of acetonitrile（A） and 0.1% phosphoric acid aqueous solution（B） at the flow rate of 0.3 mL/min. The column temperature was 30 ℃ and the detection wavelength was at 300 nm. Results Five coumarins of imperatorin， isoimperatorin， oxypeucedanin， oxypeucedanin hydrate and bergapten had good linearitys in the ranges of 0.005~0.05 μg（r=0.999 8）， 0.003~0.03 μg（r=0.999 9）， 0.002~0.02 μg（r=0.999 9）， 0.002~0.02 μg（r=0.999 1） and 0.0008~0.008 μg（r=0.999 9）. The average recovery rates were 97.00%~101.72% with RSD of 0.66%~1.52%. Conclusion The method has accurate results， simple operation， good operation， and can be used in the determination of 5 coumarins in Angelica Dahurica from Sichuan effectively.