Objective The aim of this article was to re-evaluate the methodological bias and the reliability of the conclusions of systematic reviews（SRs） of Ulcerative Colitis（UC） treated with Retention-enema of Chinese Herb. Methods CNKI， VIP， Wan Fang Database and Pubmed were electronically searched to collect the published systematic reviews and mete-analyses evaluating Ulcerative Colitis treated with Retention-enema of Chinese Herb. Results A total of 7 relevant SRs/Mets were included. The assessment results of AMSTAR2 tool showed：the quality levels of all the SRs were very low. The results of GRADE showed：the quality of the evidences of 4 outcomes were high and 1 outcome was moderate. 6 outcomes were low or very low. Conclusions The curative effect of treatment group is better than of the control group. The quality level of outcomes from moderate to high were five in total. But the methodological quality of Ulcerative Colitis treated with Retention-enema of Chinese Herb included SRs was very low， which can bring some effects on the reliability of the outcomes.