Objective To analyze the prescription of traditional Chinese medicine in the treatment of chronic urticaria based on prescription data. Methods A computer search for Chinese medicine network（CNKI）， Wanfang Medical Database，VIP Chinese Science and Technology Journal Database（VIP）， China Biomedical Literature Database（CMB）， and Pubmed database for the treatment of chronic urticaria with traditional Chinese medicine Collect the prescriptions in the literature， use Excel 2007 to build the dataset， enter the TCM heritage supporting platform software（TCMISS V 2.5）， use the data mining analysis method in the software，analyze the data， and obtain the commonly used drugs for treating chronic urticaria， high-frequency drugs. Strong drug association rules， new core combinations and new prescriptions， and draw relevant network structure diagrams for display. Results A total of 120 prescriptions were included，involving a total of 206 Chinese medicines. 64 Chinese flavors were used in the frequency of ≥6 times. The 64 Chinese medicines were mainly used as tonics， remedies and heat-clearing drugs， followed by Lishui osmotic drugs. Pinggan Xifeng medicine， promoting blood circulation and removing phlegm medicine， the medicine is cold and warm， and the taste of the medicine is mainly Xin，bitter and sweet. It mainly enters the liver， lung， spleen and stomach，and heart， and obtains 16 core combinations of Xinfang， and treats chronic phlegm. There are 8 new prescriptions for measles. Conclusion Traditional Chinese medicine treatment of chronic urticaria with “hurricane” as the core， the main use of drugs is Xin Wen Jie table，Xin Liang Jie table， nourishing blood and phlegm， clearing away heat and dampness and detoxification， supplemented by Pinggan Xifeng， blood circulation Peony.