中医外治法治疗正常高值血压的Meta分析*
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作者单位:

(1. 广西中医药大学研究生院,广西 南宁 530001;2. 广西中医药大学第一附属医院,广西 南宁 530023)

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R259

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收稿日期: 2019 - 04- 09
* 基金项目: 广西卫生厅重点课题(重2011058);广西中医药大学2019年研究生教育创新计划项目 ( YCSY20190099)
第一作者简介: 欧阳雅蓉(1994-),女,在读硕士研究生,研究方向:中西医防治心血管疾病。
△通信作者: 王庆高,E-mail:63837132@qq.com


Meta-analysis of External Therapy of Traditional Chinese Medicine for High-normal Blood Pressure
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Affiliation:

(1. Guangxi University of Chinese Medicine, Nanning 530001, China;2. The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, China)

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    摘要:

    目的系统评价针灸、耳针、艾灸、按摩、足浴、穴位埋线等中医外治法治疗正常高值血压的疗效。方法 计算机检索中国知网、维普网、万方数据库、中国生物医学文献数据库、PubMed、Embase、Cochrane Library等数据库。由2名研究员根据纳排标准独立检索并收集相关文献,使用Cochrane 评价手册对文献进行质量评估。用Revman5.1软件对所提取的数据进行Meta分析。结果 共纳入17个随机对照试验研究,包括1455例病人,其中实验组726例病人,对照组729例病人。Meta分析结果提示:与对照组相比,实验组在降低收缩压[MD=-1.30,95%CI(-1.71,-0.88),P<0.00001]、降低舒张压[MD=-3.13,95%CI(-4.16,-2.09),P<0.00001]、降压治疗效果[RR=1.13,95%CI(1.01,1.28),P=0.05]以及中医症状改善效果[RR=3.07,95%CI(1.90,4.96),P<0.00001]等方面有优势。结论 与单纯生活方式干预或不进行干预对比,中医外治法对治疗正常高值血压有效,但分析结果提示异质性大,所纳入文献质量偏低,结论可靠性仍需通过纳入样本数更大、更高质量随机临床对照试验进一步论证。

    Abstract:

    Objective To evaluate systematically the efficacy of external treatment of high-normal blood pressure by acupuncture, ear acupuncture, moxibustion, massage, foot bath and acupoint catgut embedding. Methods To search related literatures in Chinese National Knowledge Infrastructure, VIP Web, Wanfang Datebase, SinoMed, PubMed databases, Embase, and Cochrane Library. The two researchers independently and strictly searched and extracted the data according to the standard of include-exclude standard. The quality of the literatures was evaluated by using the Cochrane evaluation manual. The data were analyzed by Revman 5.1 software. Results A total of 17 randomized controlled trials including 1455 patients were included, including 726 patients in the experimental group while 729 patients in the control group. Meta-analysis result: Comparing with the control group, the experimental group had advantages in reducing systolic blood pressure[MD=-1.30, 95%CI (-1.71, -0.88), P<0.00001], diastolic blood pressure[MD=-3.13, 95%CI (-4.16, -2.09), P<0.00001], effective rate of antihypertensive therapy[RR=1.13, 95%CI (1.01, 1.28), P=0.05], and improving TCM symptoms of patients [RR=3.07, 95%CI (1.90, 4.96), P<0.00001]. Conclusion Compared with simple lifestyle intervention or no intervention, external treatment of traditional Chinese medicine is effective in the treatment of High-normal blood pressure, but the analysis results show that the heterogeneity is large, and the quality of the included literature is low. So the reliability of the conclusion still needs to be further demonstrated by the larger sample size and higher quality randomized controlled clinical trials.

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