Objective Based on the traditional Chinese medicine inheritance platform(V2.5), analyze the prescriptions of traditional Chinese medicine for the treatment of insomnia after stroke. Methods The literatures on the treatment of post-stroke insomnia by using traditional Chinese medicine prescriptions in CNKI, CBM and Wanfang database were collected, and the database was selected and established. The data mining method was explored by using TCM inheritance auxiliary system software(V2.5) to explore the prescription rules. Results A total of 102 articles were selected, involving 105 prescriptions, involving 138 flavors of traditional Chinese medicine, 10 pairs of high-frequency medicines, and 7 new prescriptions. Conclusion Insomnia after stroke treatment is mainly based on tranquilizers, supplemented by phlegm and dampness, and tonic and blood.