Abstract:Objective To systematically evaluate the effect and safety of electroacupuncture for neurogenic bladder after spinal cord injury. Methods Randomized controlled trials(RCTs) of electroacupuncture for neurogenic bladder after spinal cord injury was retrieved electronically in the Cochrane Library, Clinical Trial, Pubmed, Google Schalor, CNKI, WF Data,VIP Data before June 1, 2019. Meta-analysis was performed using RevMan 5.3 software after two researchs screened the literatures and extracted data based according to the inclusion and exclusion criteria. Results 19 RCTs involved totally 1 356 patients were included.Meta-analysis results showed that there were significant differences in clinical efficiency[RR=1.38, 95%CI(1.22, 1.56), P<0.000 01]、 maximum cystometric capacity[MD=-41.86, 95%CI(25.07, 64.53), P<0.000 0]、 maximum flow rate[MD=1.15, 95%CI(0.40, 1.89), P=0.002]、 maximum urethral closure pressure[MD=5.86, 95%CI(2.41, 9.32), P=0.000 9]、 average daily urination[MD=0.71, 95%CI(0.22, 2.31), P=0.57]; When neurogenic bladder showed urinary incontinence, the results showed that the electroacupuncture group significantly improved the residual urine volume of the bladder[MD=-14.32, 95%CI(-23.56, -5.07), P=0.002]; there was no statistically significant difference in the incidence of adverse events between the electroacupuncture group and the control group [MD=0.71, 95%CI (0.22, 2.31), P=0.57].Conclusion Electroacupuncture is effective for neurogenic bladder after spinal cord injury, including reducing bladder residual urine volume, improving the maximum bladder volume, the maximum urine flow rate, the maximum urethral closure pressure, and average daily urination, without increasing the occurrence of adverse events.